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Ritonavir or lopinavir/ritonavir drastically increase plasma concentrations of oxycodone in healthy human volunteers as a result of inhibition of CYP3A4 and CYP2D6.[fifty eight] Rifampicin significantly decreases plasma concentrations of oxycodone as a result of robust induction of CYP3A4.Prior to taking PERCOCET, inform your healthcare service pro

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